Publications by authors named "P V K Praveen"

Background: The lacrimal caruncle, a nodular structure located at the inner canthus, contains a variety of tissue types, leading to diverse clinical manifestations of its lesions. Caruncular lesions, though rare, may be benign or malignant, complicating diagnosis and treatment. This systematic review aims to provide a comprehensive overview of the clinical profiles, histopathological features, and management strategies for caruncular lesions.

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A fast and highly sensitive electrochemical sensor (ECS) is crucially desirable for observing synthetic dyes in foodstuffs, as excessive consumption of these colorants can pose risks to human health, including toxicity and pathogenicity. This research introduces the creation of an ECS comprising a CuO-ZrO nanocomposite for detecting Sunset Yellow (SY) dye in beverage and food items. The synthesized CuO-ZrO material underwent thorough characterization using various physicochemical and electroanalytical methods.

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Article Synopsis
  • Aggregation of antimicrobial peptides (AMPs) can increase their effectiveness against bacteria by disrupting their cell structures, presenting a potential solution to antibiotic resistance.
  • Researchers focused on the cephalopod Octopus bimaculoides, which lacks known AMP genes, and utilized artificial intelligence to identify four aggregation-prone peptides (Oct-P1 to Oct-P4), with Oct-P2 showing a 90% reduction in bacterial viability.
  • The study revealed that Oct-P2 not only penetrates bacterial cells but also interacts with DNA, hindering gene expression, thus illustrating its promise as a template for developing new antimicrobial therapies.
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Introduction: Reconstruction of mandibular disarticulation defects is a challenging area of head and neck surgery, with a variety of options available for replacement of the condylar head. The gold standard is autogenous reconstruction of the condyle-ramus unit. The use of a prosthetic condylar head is controversial, but in challenging cases, and those with a likely poor prognosis it may be considered and can achieve a good functional result.

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