Bidirectional strain release in a thermosalient organic salt crystal induced by anisotropic thermal expansion and phase transformation.

The jumping of crystals in the presence of external stimuli such as temperature, light, and mechanical forces is observed due to the release of accumulated strain in the crystal. Thermosalience in molecular crystals is generally induced by anisotropic thermal expansion accompanied by phase transformation. However, a thermosalient effect has not been observed in the same crystal at two different temperature zones caused by two distinct mechanisms.

G-Hemin-loaded 2D nanosheets for combined and targeted chemo-photodynamic cancer therapy.

Synergetic combination therapy is emerging as one of the most promising approaches for cancer treatment. Among the various therapeutic approaches, PDT has received particular attention due to its non-invasive nature. However, the therapeutic performance of PDT is severely affected by tumour hypoxia.

Multifunctional siRNA/ferrocene/cyclodextrin nanoparticles for enhanced chemodynamic cancer therapy.

The therapeutic outcome of chemodynamic therapy (CDT) is greatly hindered by the presence of oxidative damage repair proteins (MTH1) inside cancer cells. These oxidative damage repair proteins detoxify the action of radicals generated by Fenton or Fenton-like reactions. Hence, it is extremely important to develop a simple strategy for the downregulation of MTH1 protein inside cancer cells along with the delivery of metal ions into cancer cells.

An Observational Study on the Utility of Lab Parameters in Evaluating the Severity of Patients in South India with Covid-19.

Laboratory testing has been extremely helpful in determining the severity and determining the course of treatment for COVID-19 patients. Our aim has been to look for variables of patient's clinical and laboratory profile for two weeks and to observe their significance. Observational, Cross-sectional study.