Publications by authors named "P V Gavrilov"

Background: With the exception of the FDA-approved valrubicin and pembrolizumab, there are no standard second-line treaments for BCG-unresponsive high-risk non-muscle invasive bladder cancer (NMIBC).

Objectives: To provide a systematic review of the novel intravesically administered therapeutic agents for the salvage treatment of BCG-unresponsive NMIBC.

Methods: Online search of the PubMed, EMBASE and Web of Science databases was performed.

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Objective: To assess complications after ureteroscopy (URS) for upper tract urothelial carcinoma (UTUC) management and to assess its postoperative cumulative morbidity burden using the Comprehensive Complication Index (CCI).

Materials And Methods: Single center retrospective study including patients submitted to URS for UTUC suspicion. URSs were both diagnostic and operative.

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Kidney transplantation is the best treatment option for patients with end-stage renal disease owing to improved survival and quality of life compared with dialysis. The surgical approach to kidney transplantation has been somewhat stagnant in the past 50 years, with the open approach being the only available option. In this scenario, evidence of reduced surgery-related morbidity after the introduction of robotics into several surgical fields has induced surgeons to consider robot-assisted kidney transplantation (RAKT) as an alternative approach to these fragile and immunocompromised patients.

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Ice worlds are at the forefront of astrobiological interest because of the evidence of subsurface oceans. Enceladus in particular is unique among the icy moons because there are known vent systems that are likely connected to a subsurface ocean, through which the ocean water is ejected to space. An existing study has shown that sending small robots into the vents and directly sampling the ocean water is likely possible.

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Article Synopsis
  • * Researchers followed patients based on established guidelines and tracked recurrence-free survival for bladder cancer and UTUC, finding varying risks between low- and high-risk patients over time.
  • * Recommendations suggest that low-risk patients should undergo cystoscopy semi-annually for 24 months and annual assessments until 60 months, while high-risk patients require more frequent evaluations both for bladder and upper tract assessments.
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