[Effect of intraoperative intrapelvic chemotherapy with hyperthermia on the incidence of rectal cancer recurrences].

Often due to a severe somatic condition of the patient, the presence of perifocal inflammation, anemia, age, it is not possible to perform neoadjuvant chemoradiotherapy for rectal cancer. To improve cancer treatment outcomes in these patients intraoperative intrapelvic chemotherapy with hyperthermia is used at the Centre. In the present study there included 120 patients with rectal cancer at stage T3-4N0-2M0, while 60 patients underwent intraoperative intrapelvic chemotherapy with hyperthermia (cisplatin at a dose of 150 mg, the time of the procedure--60 minutes, the temperature of the perfusate--44-45 degrees C).

[Results of adjuvant chemotherapy (XELOX) of advanced colorectal cancer].

While the most frequent, surgery for colorectal cancer is avoided in patients with metastases to the regional lymph nodes (stage III) or distant ones (stage IV). Hence, it is being increasingly substituted with neoadjuvant treatment. Our investigation is concerned with prospective evaluation of the efficacy and toxicity profile of capecitabine (XELODA) in combination with oxaliplatin (XELOX) and adjuvant Mayo treatment (stage IIb-III).

[Proctectomy with external sphincter elements' preservation in surgery of low-ampullary rectal cancer].

Operational technique for the rectum tumors, localized at the level of dentate line, developed in the State center of coloproctology, allows preservation of external anal sphincter elements and thus, partial preservation of defecation control. Technique is described and proved, preliminary treatment results of 42 patients are analysed. The operation is oncologically effective (local recurrence rate 4,8%).

[Transanal resection of rectum with mesorectumectomy].

The possibility of sparing resection of the rectum in cancer is considered. The results of treatment in 27 patients with cancer of rectal lower ampulla (T1-10 patients, T2-12, T3-5) by transanal resection of distal part of the rectum are presented. The technique of operation, which provides the removal of all layers of rectal wall with surrounded tissues, e.

[Surgical treatment of paracolostomu hernias and prolapses].

The results of surgical treatment for paracolostomy hernias and prolapses in 71 patients show insufficient effectiveness of this method for surgical correction of such paracolostomy complications as paracolostomy hernias and prolapses: the rate of their relapses reaches 50%. The authors have developed a new effective method for surgical treatment of complicated colostomy: intraabdominal reconstruction of colostomy with retroperitoneal pull and laying of prestomal segment of the sygmoid colon.