Evaluation of contralateral arterial flow compensation using transcranial Doppler in acute internal carotid artery occlusion and implications for neurological outcome.

Acute internal carotid artery occlusion (AICAO) can result in malignant cerebral edema and unfavorable patient outcomes. This study evaluated the utility of transcranial Doppler (TCD) in assessing contralateral flow compensation and predicting outcomes in patients with AICAO. We enrolled 51 patients within 6 h of symptom onset and conducted TCD examinations to evaluate collateral circulation.

Association between chest pain and risk of depression in patients with or without coronary heart disease.

Background: Research on the relationship between chest pain and depression risk in patients with or without coronary heart disease (CHD) is limited.

Methods: This cross-sectional study includes adults in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018. The diagnoses of chest pain and CHD were based on self-reports from participants, while depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9).

Exogenous ALA applied on different plant parts promotes tomato fruit quality and GABA synthesis.

Introduction: Tomato fruit are rich in -aminobutyric acid (GABA), which lowers blood pressure and improves sleep. An increase in GABA content is important for enhancing the nutritional quality of tomato fruit.

Methods: To investigate the effects of 5-aminolevulinic acid (ALA) on fruit quality and GABA synthesis in greenhouse tomatoes, the tomato cultivar ( cv.

Effects of air pollution on the development and progression of digestive diseases: an umbrella review of systematic reviews and meta-analyses.

Air pollution, especially particulate matter (PM), is one of the most common risk factors for global burden of disease. However, its effect on the risk of digestive diseases is unclear. Herein, we attempt to explore this issue by reviewing the existing evidence from published meta-analyses.

iTASO: A Novel Photosensitive Probe for High-Throughput and Selective Submetabolomic Analysis via Flow Injection-Mass Spectrometry.

Flow injection mass spectrometry (FI-MS) is widely employed for high-throughput metabolome analysis, yet the absence of prior separation leads to significant matrix effects, thereby limiting the metabolome coverage. In this study, we introduce a novel photosensitive MS probe, iTASO-ONH, integrated with FI-MS to establish a high-throughput strategy for submetabolome analyses. The iTASO probe features a conjugated-imino sulfonate moiety for efficient photolysis under 365 nm irradiation and a reactive group for selective metabolite labeling.