Publications by authors named "P Tibbo"

People with trauma histories have an increased odds of cannabis use. Little is known about the frequency or consequences of different cannabis use regimens in cannabis users with trauma histories. Individuals with anxiety disorders tend to administer benzodiazepines in a pro re nata (PRN; i.

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Article Synopsis
  • Several trials have shown that adversity-focused treatments can reduce symptoms of PTSD and psychosis, but there is limited research on their effects on substance use, especially in early phase psychosis populations.
  • This study tested an adapted prolonged exposure therapy (PE+) on 19 adults with psychotic disorders and substance misuse, assessing multiple outcomes before and after treatment.
  • Results indicated significant improvements in some adversity-related areas and participant satisfaction, but there was no overall improvement in psychotic symptoms and substance misuse actually increased for some individuals.
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Background: Cannabidiol (CBD) impacts brain regions implicated in anxiety reactivity and stress reactivity (e.g., amygdala, anterior cingulate cortex (ACC), anterior insula (AI)); however, placebo-controlled studies are mixed regarding CBD's anxiolytic effects.

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Article Synopsis
  • Psychotic-like experiences (PLEs) are common in kids and teens and can lead to serious mental health problems later on.
  • A study of 16,560 young people found that about 17.3% had PLEs, which were linked to a higher risk of developing a psychotic disorder in early adulthood.
  • The way PLEs are assessed matters; interviews might be better at identifying those at risk for psychosis compared to self-reports, and more research is needed to understand how PLEs and other factors interact.
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