Publications by authors named "P Terragni"

Purpose: The novel coronavirus disease (COVID-19) has revived the debate on the optimal tidal volume during acute respiratory distress syndrome (ARDS). Some experts recommend 6 mL/kg of predicted body weight (PBW) for all patients, while others suggest 7-9 mL/kg PBW for those with compliance >50 mL/cmHO. We investigated whether a tidal volume ≥ 7 ml/kg PBW may be safe in COVID-19 patients, particularly those with compliance >50 mL/cmHO.

View Article and Find Full Text PDF

Multidrug-resistant organism (MDRO) outbreaks have been steadily increasing in intensive care units (ICUs). Still, healthcare institutions and workers (HCWs) have not reached unanimity on how and when to implement infection prevention and control (IPC) strategies. We aimed to provide a pragmatic physician practice-oriented resume of strategies towards different MDRO outbreaks in ICUs.

View Article and Find Full Text PDF
Article Synopsis
  • Preliminary studies indicate that extracorporeal CO removal (ECCOR) combined with Continuous Renal Replacement Therapy (CRRT) may help patients with moderate ARDS and acute renal failure, especially in the context of COVID-19, but more research is needed.
  • This study compared moderate ARDS patients with COVID-19 who received the ECCOR+CRRT treatment to a historical control group without COVID-19, using metrics like driving pressure to evaluate effectiveness.
  • Results showed a significant reduction in driving pressure in COVID-19 patients after treatment, but no differences in 28-day mortality or mechanical ventilation duration when compared to the control group, suggesting ECCOR+CRRT could be beneficial for managing respiratory pressures in these patients.
View Article and Find Full Text PDF

The effects of tracheostomy on outcome as well as on intra or post-operative complications is yet to be defined. Admission of patients with tracheostomy to rehabilitation facility is at higher risk of suboptimal care and increased mortality. The aim of the study was to investigate ICU mortality, clinical outcome and quality of life up to 12 months after ICU discharge in tracheostomized critically ill patients.

View Article and Find Full Text PDF