[Serum lipoproteins in chronic alcoholics. Changes in HDL, VLDL and LDL as a function of the degree of hepatic involvement].

Changes in lipoprotein fractions HDL and LDL-VLDL were investigated in 84 chronic alcoholic patients and attempts were made to correlate these changes with the severity of liver damage. In 40 patients with undetectable hepatic lesions the lipoprotein fractions were not reduced but a rapidly reversible increase in HDL was noted in 15%. The 14 patients with steatosis and alcoholic hepatitis showed a fall in HDL, often associated with an increase in plasma triglycerides; these changes regressed during weaning.

[Effect of long-term phenytoin treatment on the levels of calcium and magnesium in rat femurs].

In young male rats, long-term treatment with phenytoïn reduces the amount of calcium and magnesium in the femurs and provokes a stimulation of the parathyroiïds witnessed by the hypertrophy and hyperplasy of the parathyroid cells. Neither plasma calcium nor plasma and erythrocyte magnesium are modified.