Positive dementia caregiving in 30 days (PDC30): Study protocol of a randomized controlled trial of a self-guided automated online training program.

The Benefit-Finding Intervention, a face-to-face psychoeducation program with a focus on the positive meanings of caregiving, has been found to reduce depressive symptoms and burden in dementia caregivers. The program was revamped into a computer-delivered web-based program to enable 24/7 access without location restriction. This study evaluates the efficacy of this new online program called Positive Dementia Caregiving in 30 Days (PDC30).

Atherothrombotic Outcomes After Sodium-Glucose Cotransporter 2 Inhibitors Versus Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes: A Territory-Wide Retrospective Cohort Study.

Background: This study compared the risks of atherothrombotic major adverse cardiovascular events in patients with type 2 diabetes taking SGLT2 (sodium-glucose cotransporter 2) inhibitors to those taking DPP-4 (dipeptidyl peptidase-4) inhibitors.

Methods And Results: All adult patients (≥18 years of age) with type 2 diabetes and newly prescribed with SGLT2 inhibitors or DPP-4 inhibitors across all public hospitals in Hong Kong between January 2015 and December 2019 were included. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.

A long-term prospective cross-lagged study of gender-typed play and mental transformation in children.

Gender-typed play may contribute to gender disparities in spatial skills, but evidence of this link is limited. Gender-typed play and mental transformation, an important spatial skill, were studied using age-appropriate and comprehensive measures. Chinese children were tested at 5-6 years and at 11-14 years (N = 210), creating a long-term data set considering bidirectional associations.

Solid stress estimations via intraoperative 3D navigation in patients with brain tumors.

Background: Physical forces exerted by expanding brain tumors - specifically the compressive stresses propagated through solid tissue structures - reduces brain perfusion and neurological function, but heretofore has not been directly measured in patients . Solid stress levels estimated from tumor growth patterns are negatively correlated with neurological performance in patients. We hypothesize that measurements of solid stress can be used to inform clinical management of brain tumors.

A second species in the polychaete-associated crab genus Gustavus Ahyong & Ng, 2009 (Decapoda: Brachyura: Aphanodactylidae).

A second species of the previously monotypic aphanodactylid crab genus Gustavus Ahyong & Ng, 2009 is described from the Red Sea coast of Saudi Arabia. The new species, Gustavus holthuisae sp. nov.