Publications by authors named "P T Rycus"
Is there a role for extracorporeal membrane oxygenation in children with acute liver failure? A retrospective analysis of the Extracorporeal Life Support Organization Registry.
Eur J Pediatr
November 2024
Unlabelled: Data describing the use of extracorporeal membrane oxygenation (ECMO) in pediatric acute liver failure (PALF) are scarce. Thus, we aimed to describe the use of ECMO in patients with PALF using the data from the Extracorporeal Life Support Organization (ELSO) Registry between January 1, 2010, to December 31, 2022. We described patients' characteristics at ECMO initiation, outcome, and factors associated with mortality.
View Article and Find Full Text PDFAims: Current data are insufficient for the leading resuscitation societies to advise on the use of extracorporeal cardiopulmonary resuscitation (ECPR) for pediatric out-of-hospital cardiac arrest (OHCA). The aim of this study was to explore the current utilization of ECPR for pediatric OHCA and characterize the patient demographics, arrest features, and metabolic parameters associated with survival.
Methods: Retrospective review of the Extracorporeal Life Support Organization Registry database from January 2020 to May 2023, including children 28 days to 18 years old who received ECPR for OHCA.
Article Synopsis
- - Low pulse pressure (PP) during venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is linked to cardiac dysfunction and increased risk of acute brain injury (ABI), with a specific focus on central nervous system (CNS) issues.
- - An analysis of 9,807 patients showed that 15% had a low PP (≤10 mm Hg), and these patients experienced ABI more frequently (15% vs. 11%) compared to those with higher PP.
- - Low PP was independently associated with higher chances of CNS ischemia and brain death, highlighting the importance of monitoring pulse pressure in patients receiving peripheral VA-ECMO.
Article Synopsis
- The study investigates how skin pigmentation affects the discrepancy between peripheral oxygen saturation (SpO) and arterial saturation of oxygen (SaO) in patients receiving venovenous-extracorporeal membrane oxygenation (VV-ECMO), particularly focusing on race/ethnicity impacts and occult hypoxemia, linked to higher in-hospital mortality.
- Data from over 13,000 patients showed that Black and Hispanic individuals experienced higher rates of occult hypoxemia compared to White patients, with significant statistical support for these findings.
- The research highlights the need for careful monitoring of SaO in conjunction with SpO during ECMO, especially for patients with darker skin pigmentation, due to the increased risks
Objectives: Extracorporeal life support can lead to rapid reversal of hypoxemia but the benefits and harms of different oxygenation targets in severely ill patients are unclear. Our primary objective was to investigate the association between the Pa o2 after extracorporeal membrane oxygenation (ECMO) initiation and mortality in neonates treated for respiratory failure.
Design: Retrospective analysis of the Extracorporeal Life Support Organization (ELSO) Registry data, 2015-2020.