Publications by authors named "P T Koh"
Background: Universal community engagement interventions can address childhood obesity.
Objectives: This review aimed to evaluate the effectiveness of these interventions in improving body mass index (BMI) (primary outcome) as well as dietary choices and activity levels (secondary outcomes) among children and adolescents.
Methods: Eight electronic databases were searched from inception dates to January 2024.
Heterotopic pancreas - An expert in hide and seek.
Int J Surg Case Rep
November 2024
Article Synopsis
- Heterotopic pancreas is a rare condition often misdiagnosed before surgery, commonly found in the upper gastrointestinal tract, but can also occur in unusual locations such as the thorax and kidneys.
- A case study highlighted a patient with intermittent abdominal pain and weight loss, leading to the discovery of a heterotopic pancreas during surgery after imaging indicated a suspicious growth in the duodenum.
- Challenges in diagnosis include the lesion's site and characteristics; while biopsies can help, they are often non-diagnostic, and the only definitive treatment is surgical resection.
Article Synopsis
- Hepatocellular carcinoma (HCC) is a dangerous type of cancer that is different inside each tumor, making it hard to treat.
- Researchers studied over 600 samples from 123 patients to understand how this cancer develops and progresses.
- They discovered that the most aggressive cells in a tumor are the best way to predict how well a patient will do, not just by looking at how different the tumor cells are from each other.
Ischemic stroke causes a lack of oxygen and glucose supply to brain, eventually leads to severe neurological disorders. Retinoic acid is a major metabolic product of vitamin A and has various biological effects. The PI3K-Akt signaling pathway is an important survival pathway in brain.
View Article and Find Full Text PDFBackground: Extended pleurectomy decortication for complete macroscopic resection for pleural mesothelioma has never been evaluated in a randomised trial. The aim of this study was to compare outcomes after extended pleurectomy decortication plus chemotherapy versus chemotherapy alone.
Methods: MARS 2 was a phase 3, national, multicentre, open-label, parallel two-group, pragmatic, superiority randomised controlled trial conducted in the UK.