Saline at lower tonicity in cystic fibrosis (SALTI-CF) trial comparing 0.9% 3% 6% nebulised saline.

Background: In people with cystic fibrosis (CF), regular nebulisation of 6% or 7% saline improves lung function; however, these concentrations are not always tolerable. Clinically, some CF patients report using lower concentrations of saline to improve tolerability, yet the effects of lower concentrations are unknown. This study therefore aimed to evaluate the relative effectiveness and tolerability of 0.

Knowledge to action: Resilience planning among state and local transportation agencies in the United States.

The results of a nationwide survey of state and local agencies conducted in 2020 are summarized to understand priorities for improving transportation emergency management (EM) and resilience. Questions on EM activities, policies, and operations were answered by 190 respondents from across the country. In addition to comparing responses across transportation, EM, and other organizations (law enforcement, public works, health, environmental services, etc.

Effect of -Acetylcysteine in Combination with Antibiotics on the Biofilms of Three Cystic Fibrosis Pathogens of Emerging Importance.

Cystic fibrosis (CF) is a genetic disorder causing dysfunctional ion transport resulting in accumulation of viscous mucus that fosters chronic bacterial biofilm-associated infection in the airways. and are increasingly prevalent CF pathogens and while is slowly decreasing; all are complicated by multidrug resistance that is enhanced by biofilm formation. This study investigates potential synergy between the antibiotics ciprofloxacin (0.

Elicitation interview study to identify salient beliefs about exercise participation in adults with cystic fibrosis.

Objectives: Conduct an elicitation study, using the Theory of Planned Behaviour framework, to identify salient beliefs about exercise participation in adults with cystic fibrosis (CF). Specifically, identify attitudes on advantages and disadvantages of exercise (behavioural beliefs); individuals and groups who apply social pressure to exercise (normative beliefs); and perceived control over facilitators and barriers to exercise (control beliefs) for adults with CF.

Design: Qualitative interviews using open-ended, structured questions.

Management of Australian Adults with Bronchiectasis in Tertiary Care: Evidence-Based or Access-Driven?

Purpose: Australian data regarding the management of patients with bronchiectasis is scarce. We sought to compare the management of adults with bronchiectasis attending tertiary Australian centres with recent national and international guidelines.

Methods: The Australian Bronchiectasis Registry is a centralised database of patients with radiologically confirmed bronchiectasis unrelated to cystic fibrosis recruited from 14 tertiary Australian hospitals.