Unlabelled: Gastroesophageal reflux disease (GERD) is one of the most common disorders of the gastrointestinal tract. Reflux oesophagitis is observed in about 30-50% of GERD patients. Factors leading to development of mucosal damage remain still unclear.
View Article and Find Full Text PDFUnlabelled: Met-enkephalin is a pentapeptide belonging to the opioid system and like other opioid peptides is involved in phenomena associated with modulated pain perception, regulation of memory and emotional conditions, food and liquid consumption, regulation of immunological system and it has an impact upon digestive system motility, gastric and pancreatic secretion, metabolism of carbohydrates. Met-enkephalin concentration changes in liver tissue and plasma during liver disorders. It has been revealed that Met-enkephalin takes part in the etiopathogenesis of ascites and pruritus.
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December 2001
Unlabelled: The oesophageal inflammation during gastrointestinal reflux disease (GERD) has been considered to be an acid and pepsine related disorder. The oesophagus remains under the prolonged exposure of gastric acid, which damages the mucosa and causes an esophagitis. Amongst the most important pathogenetic factors of GERD, the delayed gastric emptying and transient episodes of low esophageal sphincter (LES) relaxation have been described.
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