Publications by authors named "P Szapary"
Article Synopsis
- Scientists believe that delivering special medicines directly into tumors could help fight cancer better.
- An expert group worked together to figure out how to create better tests for these new treatments, including which patients to help.
- They discussed different ideas on how to design these tests, so they can learn the most about how well the new therapies work for different types of cancer.
Rationale: Stereotactic body radiation therapy (SBRT) is the standard of care for inoperable early stage non-small cell lung cancer (NSCLC). Use of image guided thermal ablation (IGTA; including microwave ablation [MWA] and radiofrequency ablation [RFA]) has increased in NSCLC, however there are no studies comparing all three.
Objective: To compare the efficacy of IGTA (including MWA and RFA) and SBRT for the treatment of NSCLC.
Studies of bronchoscopy have reported diagnostic yield (DY) using different calculation methods, which has hindered comparisons across studies. To quantify the effect of the variability of four methods on DY estimates of bronchoscopy. We performed a simulation-based analysis of patients undergoing bronchoscopy using variations around base case assumptions for cancer prevalence (60%), distribution of nonmalignant findings, and degree of follow-up information at a fixed sensitivity of bronchoscopy for malignancy (80%).
View Article and Find Full Text PDFBackground: Image-guided percutaneous thermal ablation is an established treatment option for early-stage lung cancer in medically inoperable patients but carries a high risk of pleura-related complications, particularly pneumothorax.
Objective: This study aimed to determine if image-guided transbronchial microwave ablation (tMWA) is a feasible approach to treat peripheral stage 1 lung cancer.
Method: A prospective, single-arm, multicenter study sought to enroll 40 adults who were medically inoperable or declined surgery for peripheral stage 1 lung tumors (≤20 mm).