Background: There is paucity of information on the role of cytomegalovirus (CMV) infection as a cause of stillbirths or childhood deaths in low-and middle-income countries (LMICs). We investigated attribution of CMV-disease in the causal pathway to stillbirths and deaths in children <5 years of age in seven LMICs participating in the Child Health and Mortality Prevention Surveillance (CHAMPS) network.
Methods: We analyzed stillbirths and decedents enrolled between December 2016 and July 2023.
Proc Natl Acad Sci U S A
February 2025
The Red Sea, a nascent ocean basin connected to the Indian Ocean via a shallow strait, is assumed to have experienced significant environmental changes during the last glacial period due to a sea-level drop likely exceeding 110 m. This study investigates the hypothesis that hydrodynamic restriction led to severe ecological impacts, including basin-wide extinction due to elevated salinity followed by a short time of oxygen depletion. Uranium-Thorium dating of deep-water corals (DWCs) from 26 northern Red Sea sites reveals coral growth during and after the Last Glacial sea-level lowstand, indicating tolerable seawater chemistry.
View Article and Find Full Text PDFIntroduction: Common mental disorders, such as anxiety disorders, depression, and posttraumatic stress disorder (PTSD), present a substantial health and economic burden. The gut microbiome has been associated with these psychiatric disorders via the microbiome-gut-brain axis. However, previous studies have focused on the associations between the gut microbiome and common mental disorders in European, North American, and Asian populations.
View Article and Find Full Text PDF: Airway care interventions and prone positioning are used in critically ill patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU) to improve oxygenation and facilitate mucus removal. At the onset of the COVID-19 pandemic, the decision-making process regarding the practice of airway care interventions and prone positioning was challenging. To provide an overview of the practice of airway care interventions and prone positioning during the second wave of the pandemic in the Netherlands.
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