Publications by authors named "P Stephens"
Purpose: Lack of knowledge contributes to disparate outcomes among Americans with asthma or chronic obstructive pulmonary disease (COPD). This study assessed the impact of an educational intervention on disease knowledge and management in Black Americans with asthma or COPD.
Design: Pre-post study design with 9-month follow-up.
There are a number of new format antibody-inspired molecules with multiple antigen binding capabilities in development and clinical evaluation. Here, we describe the impact of the sequence and configuration of a unique bispecific antibody format (termed BYbe) using a panel of four BYbe's and the three IgG1s from which they were derived on their production in a Chinese hamster ovary (CHO) cell expression system. Following transfection and selection, one bispecific antibody format yielded fewer mini-pools in comparison to the other bispecific cell pools.
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- - Anthropogenic changes to landscapes are creating new ecological boundaries that are linked to increased outbreaks of zoonotic diseases, yet the reasons for these new emergence events are not well understood.
- - The study investigates how two types of ecosystem boundaries—biotic transition zones and land use transition zones—affect the risk of disease spillover, using ebolavirus and its reservoir (bats) and accidental host (primates) as a model.
- - Findings reveal that areas where species ranges overlap and where habitat diversity is high increase the risk of ebolavirus outbreaks, while gradual transition zones with rangelands may actually help reduce this risk.
Black patients with tetralogy of Fallot (TOF) have higher mortality than White patients. Health disparities related to other patient-important outcomes, such as exercise performance, have not been studied in this population. We aimed to determine if there are racial disparities related to exercise performance in patients with TOF and to investigate possible mediators of those disparities.
View Article and Find Full Text PDFGlobally, human-wildlife conflicts continue to increase, owing to human population growth and expansion. Many of these conflicts concern the impacts of invasive non-native species. In the UK, the invasive, non-native grey squirrel Sciurus carolinensis negatively affects tree health and has caused the decline of the native red squirrel Sciurus vulgaris.
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