Publications by authors named "P Steiger"
Article Synopsis
- The study investigated whether volatile sedation with sevoflurane could protect organs in patients with severe COVID-19 lung injury experiencing a cytokine storm, particularly focusing on IL-6 levels.
- Conducted as a pilot trial in Switzerland, 60 patients requiring mechanical ventilation were randomly assigned to receive either sevoflurane or continuous intravenous sedation, with their outcomes analyzed at 28 days.
- Results showed no significant difference in primary outcomes such as mortality or persistent organ dysfunction between the two groups, but the sevoflurane group required fewer vasopressors and had higher reported acute kidney injury rates compared to controls.
Background: Patients in burns centres are at high risk of acquiring multi-drug-resistant organisms (MDROs) due to the reduced skin barrier and long hospital stay.
Methods: This study reports the investigation and control of an outbreak of MDR Acinetobacter baumannii in a burns centre. The 27 patients hospitalized in the centre during the outbreak were screened regularly, and a total of 132 environmental samples were analysed to identify a potential source.
Objectives: Bromelain-based enzymatic debridement has emerged as a valuable option to the standard surgical intervention for debridement in burn injuries. Adverse effects on coagulation parameters after enzymatic debridement have been described. The purpose of this study was to compare the effect of enzymatic and surgical debridement on coagulation.
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- Hypothermia in severely burned patients can significantly increase the risk of complications and mortality, making effective temperature management crucial during surgery.
- A study at the University Hospital Zurich evaluated the use of an oesophageal heat exchanger tube (EHT) for perioperative warming in patients with severe burns (TBSA over 30%) and found it increased body temperature by 0.07°C per minute, significantly better than standard management which resulted in temperature loss.
- The results support using EHT as a primary method for managing body temperature during surgery in severe burn cases, showing it is effective and safe, potentially reducing complications related to hypothermia.