Publications by authors named "P Stanley"

Article Synopsis
  • - Glycosylation-deficient CHO cell lines, specifically Lec5 and Lec9, have been key to understanding N-glycosylation, but the reasons behind their glycosylation defects remained unclear until now.
  • - Dolichol synthesis from polyprenol was found to occur in three steps involving the enzymes DHRSX and SRD5A3, with Lec5 and Lec9 cells showing increased levels of polyprenol and decreased dolichol, indicating a deficiency in DHRSX.
  • - Long-read genome sequencing revealed that the DHRSX gene was missing in Lec5 and Lec9 cells, while the SRD5A3 gene was intact, confirming that the glycosylation defects
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Identifying factors required for spermatogenesis is important for understanding mechanisms of male fertility. Inactivation of either the or gene leads to a block in spermatogenesis causing infertility in male mice. MGAT1 GlcNAc-transferase initiates complex N-glycan synthesis and MAN2A2 mannosidase generates the substrate for MGAT2 GlcNAc-transferase to form a biantennary complex N-glycan.

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Designing multifunctional materials that mimic the light-dark decoupling of natural photosynthesis is a key challenge in the field of energy conversion. Herein, we introduce MnBr-253, a precious metal-free metal-organic framework (MOF) built on Al nodes, bipyridine linkers and MnBr(CO)(bipyridine) complexes. Upon irradiation, MnBr-253 colloids demonstrate an electron photocharging capacity of ~42 C ⋅ g , with state-of-the-art photocharging rate (1.

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Grazing lands play a significant role in global carbon (C) dynamics, holding substantial soil organic carbon (SOC) stocks. However, historical mismanagement (e.g.

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