Publications by authors named "P Speelman"
Article Synopsis
- Coral reefs are increasingly threatened by climate change, particularly from mass bleaching events, making it essential to understand their recovery mechanisms.
- Contrasting responses were observed between intertidal and subtidal coral communities in the Kimberley region after a 2016 global bleaching event: intertidal corals showed resilience, while many subtidal corals perished.
- Three and a half years post-bleaching, changes in coral community composition were identified, with subtidal areas dominated by opportunistic, weedy corals, suggesting that varying heat tolerance on spatial scales significantly affects recovery and community dynamics.
Aim: To develop a framework for the clinical and health economic assessment for management of Clostridium difficile infection (CDI).
Methods: CDI has vast economic consequences emphasizing the need for innovative and cost effective solutions, which were aim of this study. A guidance model was developed for coverage decisions and guideline development in CDI.
[New treatment options for infections with Clostridium difficile].
Ned Tijdschr Geneeskd
August 2014
Currently available broad spectrum antibiotics are not sufficiently effective against recurrent Clostridium difficile infections (CDI). Donor faecal microbiota transplantation is a very effective treatment for second and recurrent infection but is time-consuming and requires careful screening of donors. The new narrow spectrum antibiotic fidaxomicin is a good alternative in a first CDI or a first recurrence, but treatment is expensive and there are no data on its effectiveness in a second or later recurrence.
View Article and Find Full Text PDFPurpose Of Review: To review the current evidence on fecal microbiota transplantations (FMTs) for recurrent Clostridium difficile infections (CDIs), metabolic syndrome and inflammatory bowel disease.
Recent Findings: Recently, a randomized trial confirmed the efficacy of this treatment strategy in patients with recurrent CDI. For other disorders, evidence is still limited.
Background: Recurrent Clostridium difficile infection is difficult to treat, and failure rates for antibiotic therapy are high. We studied the effect of duodenal infusion of donor feces in patients with recurrent C. difficile infection.
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