Publications by authors named "P Souteiro"
Non-functional alpha-cell hyperplasia with glucagon-producing NET: a case report.
Front Endocrinol (Lausanne)
September 2024
Article Synopsis
- Alpha-cell hyperplasia (ACH) is a rare pancreatic condition with various forms and is often associated with pancreatic neuroendocrine tumors (pNETs), although its causes are not well understood.
- A 72-year-old male with type 2 diabetes was found to have a non-functioning pNET during treatment for gallbladder issues, which revealed mild glucagon elevation and led to surgery.
- Pathological analysis showed the pNET was glucagon-producing and occurred alongside ACH, emphasizing the need for specialized testing to diagnose such cases even when symptoms suggest a non-functioning tumor.
Article Synopsis
- Composite pheochromocytoma (CP) is a rare tumor found in the adrenal glands, combining elements of pheochromocytoma and neuroblastoma, with limited information available about it.
- A case study detailed a 56-year-old woman with CP containing a ganglioneuroma, contributing to a literature review that identified 110 total cases, with a median age of 51.5 and a majority being female.
- Genetic syndromes related to CP were found in 20% of cases, with the most common being neurofibromatosis type 1, and the review emphasized that most neuroblastic components were ganglioneuromas, while only a small percentage of patients experienced metastasis or
Objectives: Therapeutic options for pancreatic neuroendocrine neoplasia (Pan-NEN) have increased over the last decade. We aim to understand the evolution of the prognosis of patients with diagnosis of Pan-NEN within a 12-year period, considering the implementation of new treatments.
Methods: This study is a retrospective cohort study of patients diagnosed with Pan-NENs between 2006 and 2017.
Male gender as a poor prognostic factor in medullary thyroid carcinoma: behavior or biological difference?
Minerva Endocrinol (Torino)
December 2023
Background: Due to the low incidence and heterogeneous behavior of medullary thyroid carcinoma (MTC), its prognostic factors are still not well stablished. While several large studies have investigated the impact of gender in differentiated thyroid cancer (DTC), its role in MTC outcomes remains controversial. We aim to identify MTC prognostic features, specially focusing on the role of gender.
View Article and Find Full Text PDFIntroduction: Current guidelines specify controversial areas in adrenocortical carcinomas (ACC), such as optimal follow-up time after remission and identification of prognostic markers. We aim to address these topics by analyzing four reference centers in our country.
Methods: Cross-sectional multicentric study of 69 patients (mean age: 51.