Publications by authors named "P Sorajja"

Background: The association, if any, between the transmitral mean pressure gradient (TMPG) after mitral transcatheter edge-to-edge repair and 1-year mortality is controversial in patients undergoing mitral transcatheter edge-to-edge repair with the MitraClip system. We sought to estimate the association between intraoperatively measured residual mitral regurgitation (rMR) and TMPG and 1-year mortality among patients undergoing mitral transcatheter edge-to-edge repair to facilitate decisions on additional devices.

Methods: In patients with severe secondary (functional) MR, we analyzed registry data using generalized estimating equations.

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Article Synopsis
  • Untreated severe tricuspid regurgitation (TR) is linked to poor health outcomes, making effective treatment essential.
  • The study evaluated the 1-year results of transcatheter edge-to-edge repair (TEER) using the TriClip system in patients with complex tricuspid valve issues, finding significant improvements in patient survival and quality of life.
  • Results showed that 81% of patients experienced a reduction in TR to moderate or less after one year, with no major adverse effects noted in the first 30 days post-procedure.
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  • The study focuses on the impact of tricuspid regurgitation (TR) on heart remodeling, comparing outcomes in patients treated with the TriClip device versus those receiving standard medical therapy in a randomized controlled trial.
  • Researchers utilized advanced imaging techniques, including cardiac magnetic resonance and 4D-CT, to assess heart changes at baseline, 30 days, and one year follow-ups.
  • Results showed that the TriClip significantly reduced TR volume by 70% at 30 days, leading to notable reductions in right ventricular size and area, with these improvements maintained after one year, unlike the control group.
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Article Synopsis
  • - The TRILUMINATE Pivotal trial assessed the effects of tricuspid transcatheter edge-to-edge repair (T-TEER) on reducing tricuspid regurgitation (TR), a significant heart condition linked to increased health risks.
  • - Involving 572 patients, mostly elderly women with prior heart conditions, the trial found that T-TEER effectively improved quality of life, with nearly half of those treated experiencing significant improvements in heart health assessments.
  • - Results showed that while the treatment and control groups had similar rates of survival and heart-related surgeries, those who underwent T-TEER had notably better outcomes in TR severity and overall quality of life.
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Background: Assessment of coronary artery disease (CAD) is critical in managing severe aortic stenosis. Unplanned coronary angiography after TAVR, with or without percutaneous coronary intervention, may present significant challenges.

Objectives: The aim of this study was to evaluate the incidence, predictors, and outcomes of unplanned coronary angiography after transcatheter aortic valve replacement (TAVR).

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