Publications by authors named "P Socha"
Background: There is a lack of studies evaluating longitudinal changes in adiposity indicators and the association with 24-hour movement behavior guidelines in preschoolers. Therefore, this study aimed to investigate associations between changes in Body Mass Index (BMI) z-scores, waist circumference and waist-to-height ratio, and compliance with the 24-hour movement behavior guidelines in three- to six-year-old children from a European sample.
Methods: In total, data from a European sample of 719 preschoolers (50.
Article Synopsis
- Oclacitinib (OCL) is a Janus kinase inhibitor approved for treating atopic dermatitis (AD) in dogs, and this study aimed to evaluate its effects on T cell populations and safety in affected dogs.
- After 28 days of treatment with OCL, certain T cell counts (CD4 and CD8) showed no significant changes compared to baseline, although an increase was noted on day 7, followed by a decrease in specific subsets on days 14 and 28.
- The study concluded that OCL treatment appears safe regarding T cell counts and suggests its therapeutic benefits may come from lowering eosinophil levels and reducing CD25 expression on CD4 Teff cells linked to AD.
Background: Multiparametric MRI markers of liver health corrected T1 (cT1) and proton density fat fraction (PDFF) have shown utility in the management of various chronic liver diseases. We assessed the normal population reference range of both cT1 and PDFF in healthy child and adult volunteers without any known liver disease.
Methods: A retrospective multi-centre pooled analysis of 102 child and young adult (9.
Introduction: How bacterial infections of the reproductive tract cause infertility and the correlation between the health status of female dogs and the presence of () in the vagina are still unclear. The aim of this study was to determine the population in the vagina of breeding bitches and to correlate this microbial population with some fertility outcomes.
Material And Methods: A total of 275 breeding bitches were included in the study.
Article Synopsis
- * Researchers identified 38 genes that influence αSyn propagation, focusing on two genes, which help understand how αSyn interacts with lipids and forms inclusions resembling Lewy Bodies.
- * Analysis of gene expression changes after manipulating these genes revealed a connection to increased risk variants in Parkinson's patients, supporting a model where genetic factors disrupt αSyn regulation, leading to disease progression.