Publications by authors named "P Sobierajska"

This paper discusses the origin of emission quenching in yttrium orthovanadate codoped with Eu and Sb ions. Highly crystalline yttrium orthovanadate nanoparticles with chemical composition YEuSbVO ( = 0-5.4 mol %, = 0-2.

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Article Synopsis
  • Hydroxyapatite is commonly used in medicine for repairing and regenerating tissues, and doping it with silver enhances its antimicrobial properties.
  • In the study, various types of silver-doped nanohydroxyapatite were synthesized and analyzed, confirming their hydroxyapatite structure and the presence of essential elements through several scientific techniques.
  • The results indicated that silver-doped hydroxyapatite nanoparticles exhibit significant antibacterial and antifungal activity against various bacterial and fungal strains compared to pure hydroxyapatite.
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The aim of this research was to investigate the photothermal ability of nanocrystalline hydroxyapatite (nHAp) incorporated with silver and gold. It was studied by using a recently developed technique evaluating the photothermal conversion efficiency. The heating performance of aqueous dispersions was examined under 445 and 532 nm excitation.

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This study reports an impact of structure (XRPD, FT-IR) and surface morphology (SEM-EDS) of imatinib-functionalized galactose hydrogels, loaded and unloaded with nHAp, on osteosarcoma cell (Saos-2 and U-2OS) viability, levels of free oxygen radicals, and nitric oxide, levels of BCL-2, p53, and caspase 3 and 9, as well as glycoprotein-P activity. It was investigated how the rough surface of the crystalline hydroxyapatite-modified hydrogel affected amorphous imatinib (IM) release. The imatinib drug effect on cell cultures has been demonstrated in different forms of administration-directly to the culture or the hydrogels.

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Article Synopsis
  • The study explored the antibacterial activity and biocompatibility of nanohydroxyapatites (nHAp) doped with copper and zinc ions in various forms, including nanopowder, hydrogel, and pellets.
  • Results showed that copper ions were effectively released and exhibited moderate to significant antimicrobial activity against bacterial strains, particularly Pseudomonas aeruginosa.
  • The biocompatibility tests indicated that the materials were safe for normal mouse and human cells, demonstrating no harmful effects on red blood cells, confirming their potential application in biomedical fields.
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