Publications by authors named "P Sinnappurajar"
Background: In settings with universal conjugate pneumococcal vaccination, invasive pneumococcal disease (IPD) can be a marker of an underlying inborn error of immunity. The aim of this study was to determine the prevalence and characterize the types of immunodeficiencies in children presenting with IPD.
Methods: Multicenter prospective audit following the introduction of routinely recommended immunological screening in children presenting with IPD.
Article Synopsis
- - Adalimumab and its biosimilar Amgevita were compared for their effectiveness and tolerability in treating non-infectious uveitis across three UK medical centers.
- - In a study involving 102 patients, the rates of uveitis flare after switching to Amgevita were similar to those before switching, although intraocular pressure improved.
- - Despite the non-inferiority of Amgevita to Humira, 24% of participants chose to revert to Humira, often due to discomfort from injections and difficulties with the new delivery device.