Publications by authors named "P Simpson"
Background: During the COVID-19 pandemic, outpatient waits for gynaecology appointments increased by 60% in the UK National Health Service (NHS). The aim of this study was to use the electronic Personal Assessment Questionnaire-Menstrual, Pain and Hormonal (ePAQ-MPH) electronic patient reported outcome measure (ePROM) to assess symptoms, impact and potential harm for patients waiting > 60 weeks for general gynaecology appointments at a teaching hospital.
Methods: 1070 patients waiting > 60 weeks for a new appointment (range 60-72 weeks) were invited to complete ePAQ-MPH online to measure gynaecological symptoms and health-related quality-of-life (HRQoL).
: variants are the most well-known genetic risk factor (10%) for hypoplastic left heart syndrome (HLHS) and are associated with decreased cardiac transplant-free survival. encodes for α-myosin heavy chain (α-MHC), a contractile protein expressed in the neonatal atria. We therefore assessed atrial function in HLHS patients with variants.
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- The study explores the emerging field of epidemiological criminology, focusing on the relationship between public health and justice systems, while identifying knowledge gaps in existing research.
- By analyzing 34,481 PubMed abstracts from 1963 to 2023, the study highlights that nearly half of these abstracts lack population characteristic details, with only a small percentage providing comprehensive demographic information.
- Findings reveal a significant increase in research on female populations, which now surpasses that on males, raising concerns about the underrepresentation of male prisoners in studies, despite them making up the majority of the incarcerated population.
Updating behavior based on feedback from the environment is a crucial means by which organisms learn and develop optimal behavioral strategies. Norepinephrine (NE) release from the locus coeruleus (LC) has been shown to mediate learned behaviors such that in a task with graded stimulus uncertainty and performance, a high level of NE released after an unexpected outcome causes improvement in subsequent behavior. Yet, how the transient activity of LC-NE neurons, lasting tens of milliseconds, influences behavior several seconds later, is unclear.
View Article and Find Full Text PDFPurpose: Cognitive functional therapy (CFT) is an individualised person-centred biopsychosocial intervention that demonstrated large and sustained clinically important improvements in people with chronic, disabling low back pain (LBP) in the RESTORE randomised controlled trial. This study aimed to explore physiotherapists' experiences of delivering CFT in the RESTORE trial.
Materials And Methods: Cross-sectional qualitative design using reflexive thematic analysis with interviews of 15 treating physiotherapists (3-25 years experience) across Perth and Sydney.