Publications by authors named "P Silvi Antonini"
Aims: This study aimed to conduct a phase 2 proof-of-concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non-neutralizing humanized monoclonal antibody targeting the N-terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart failure (AHF).
Methods And Results: This prospective, open-label, controlled, interventional, multicenter, dose-escalation study was conducted at two cardiology sites in Indonesia. Patients were divided into two interventional groups sequentially receiving 0.
Article Synopsis
- * Two vaccines are available: Dengvaxia®, which is not recommended for travelers, and Qdenga®, which is now licensed for travelers in several European countries, including Switzerland.
- * The Swiss Expert Committee for Travel Medicine advises that Qdenga® should not be given to those without prior dengue infection, but may be suitable for travelers aged 6 and older who have proof of past infection and are going to areas with high dengue transmission.
Article Synopsis
- Identical translocations involving the TFE3 gene have been linked to various tumors, including specific renal and soft tissue cancers like alveolar soft part sarcoma and clear cell stromal tumor of the lung.
- This review focuses on the clinicopathologic and molecular characteristics of TFE3-rearranged renal tumors, highlighting the complexity in their classification due to differing tumor types and features.
- While the reason for the diverse morphologies associated with similar gene fusions remains unclear, the pathology community still supports maintaining distinct classifications for TFE3-rearranged renal cell carcinoma and TFE3-rearranged PEComa.
Article Synopsis
- Melanoma in situ of the nipple is rare and not well-documented, making diagnosis difficult due to various potential conditions affecting the nipple-areola area.
- A case is presented of a patient with cosmetic bilateral breast implants who reported eczema on her left nipple-areola complex and had suspicious microcalcifications found on a mammogram.
- The patient was ultimately diagnosed with nipple melanoma and also had ductal carcinoma in situ in the same breast.