Publications by authors named "P Siegrist"
Article Synopsis
- "Full moon" calcification in coronary arteries represents a blockage detectable via coronary computed tomography angiography (CCTA) and is linked to poorer outcomes in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
- In a study of 140 patients undergoing elective CTO-PCI, those with "full moon" calcification were older and exhibited higher cardiovascular risks, with a significantly greater failure rate to cross the lesion compared to patients without this morphology (53.5% vs 12.5%).
- The study employed multivariable logistic regression to assess factors influencing procedural success, finding full moon calcification significantly correlated with higher incidences of complications like chronic kidney failure and previous coronary artery bypass surgery.
Background: Clinical outcomes and treatment selection after completing the randomized phase of modern trials, investigating antiplatelet therapy (APT) after percutaneous coronary intervention (PCI), are unknown.
Objectives: The authors sought to investigate cumulative 15-month and 12-to-15-month outcomes after PCI during routine care in the MASTER DAPT trial.
Methods: The MASTER DAPT trial randomized 4,579 high bleeding risk patients to abbreviated (n = 2,295) or standard (n = 2,284) APT regimens.
Background: Polymer-free drug-coated stents aim to avoid the inflammatory potential of durable polymers, thereby improving the long-term safety profile, and allowing a shorter duration of dual antiplatelet therapy.
Aims: The BIOVITESSE study was conducted to assess the safety and clinical performance of the BIOrapid polymer-free coronary stent system coated with a novel highly lipophilic sirolimus derivate.
Methods: BIOVITESSE was a prospective, multicentre, first-in-man study that enrolled subjects with de novo coronary lesions in two cohorts of 33 patients each.
The Role of Percutaneous Coronary Revascularization in Chronic Coronary Syndromes Coronary heart disease represents the leading cause of morbidity and mortality worldwide. Optimal management of these patients is therefore crucial and includes lifestyle changes, optimal medical therapy, and coronary revascularization. This review summarizes diagnostic and therapeutic strategies of patients with chronic coronary syndromes, focusing on the 2019 European Society of Cardiology (ESC) guidelines for the diagnosis and management of chronic coronary syndromes.
View Article and Find Full Text PDF