Publications by authors named "P Sgro"
Muscle tissue is an important target of sex steroids, and particularly, testosterone plays essential roles in muscle cell metabolism. Wide ranges of studies have reported sex differences in basal muscle steroidogenesis, and recently several genes have been identified to be regulated by androgen response elements that show innate sex differences in muscle. However, studies accounting for and demonstrating cell sexual dimorphism in vitro are still scarce and not well characterized.
View Article and Find Full Text PDFCancer remains a major challenge in medicine, prompting exploration of innovative therapies. Recent studies suggest that exercise-derived extracellular vesicles (EVs) may offer potential anti-cancer benefits. These small, membrane-bound particles, including exosomes, carry bioactive molecules such as proteins and RNA that mediate intercellular communication.
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- Breast cancer (BC) is a major global health issue for women, and studies show that physical activity (PA) can significantly improve quality of life, recovery, and survival rates in BC patients.
- PA affects DNA methylation, potentially reversing abnormal patterns linked to cancer and other diseases, and this review highlights how PA influences both global and gene-specific DNA methylation in BC patients.
- The analysis indicates that PA can elevate global DNA methylation in tumors and affects various genes associated with important biological processes, underscoring its potential to restore normal cell function and improve recovery and survival outcomes for BC patients.
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- Whole-body vibration (WBV) is explored for enhancing muscular endurance and its neural mechanisms but has seen limited research on its impact on torque signal complexity.
- In a study involving thirty males, the effects of WBV were compared with static half squats and no exercise regarding maximal torque, fatigue, and signal complexity during an endurance task.
- Results showed that WBV did not improve maximal torque production or knee extensors fatigability and might actually have detrimental effects compared to other conditions.
is widely grown throughout the tropics and increasingly used for its therapeutic and nutraceutical properties. These properties are attributed to potent antioxidant and metabolism regulators, including glucosinolates/isothiocyanates as well as flavonoids, polyphenols, and phenolic acids. Research to date largely consists of geographically limited studies that only examine material available locally.
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