Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women.

Context: Human adipose tissue produces several adipokines, including the newly identified protein cathepsin S (CTSS), a cysteine protease involved in the pathogenesis of atherosclerosis. Obesity is characterized by high levels of CTSS in the circulation and in sc white adipose tissue (scWAT).

Objective: We investigated the effect of surgery-induced weight loss on circulating CTSS and its protein expression in scWAT.

[Laparoscopic treatment of perforated duodenal ulcer].

Objective: The aim of this study was to determine if laparoscopic simple closure for perforated duodenal ulcer is possible, efficient and safe.

Methods: Thirty-five consecutive patients with perforated duodenal ulcer and peritonitis were treated by simple closure, peritoneal lavage and omentoplasty. This treatment was performed laparoscopically.

[The thromboembolic risk in abdominal plastic surgery. A randomized statistical study of 190 cases].

The authors studied the risk of thromboembolism in a randomized study of 190 abdominoplasties. In this study, none of the classical risk factors (weight, operating time, weight of the surgical specimen, combined surgery) were significant. Only contention associated with anticoagulants (low molecular weight heparin) decreased this risk to 2.

[Laparoscopic appendectomy in the adult].

Aim Of The Study: The benefits of laparoscopic appendectomy remain controversial. The aim of the study was to evaluate the advantages and disadvantages of this technique.

Material And Methods: Four hundred and forty-eight patients operated on for suspected appendicitis during a 5-year period were analysed in a retrospective study.