Publications by authors named "P Sebo"
Geographical Disparities in Research Misconduct: Analyzing Retraction Patterns by Country.
J Med Internet Res
January 2025
This study examines disparities in research retractions due to misconduct, identifying countries with the highest retraction counts and those disproportionately represented relative to population and publication output. The findings emphasize the need for improved research integrity measures.
View Article and Find Full Text PDFUse of ChatGPT to Explore Gender and Geographic Disparities in Scientific Peer Review.
J Med Internet Res
December 2024
Article Synopsis
- Peer review is essential for ensuring the quality of scientific papers, and recent trends are promoting transparency by publishing peer-review reports alongside articles.
- The study used ChatGPT-4 to analyze sentiment and politeness in peer-review reports from high-impact medical journals, focusing on gender and geographical differences to foster inclusivity in the process.
- Results indicated that peer-review reports from the Middle East, Latin America, and Africa scored lower in sentiment and politeness compared to those from North America and Europe, while no significant gender differences were found among authors.
Whole-cell pertussis (wP) vaccines introduced in the 1940s led to a dramatic reduction of pertussis incidence and are still widely used in low- and middle-income countries (LMICs) worldwide. The reactogenicity of wP vaccines resulted in reduced public acceptance, which drove the development and introduction of acellular pertussis (aP) vaccines in high-income countries in the 1990s. Increased incidence of pertussis disease has been observed in high-income countries following the introduction of aP vaccines despite near universal rates of pediatric vaccination.
View Article and Find Full Text PDFValidity of a four-item questionnaire in French assessing attachment to meat.
Front Med (Lausanne)
October 2024
Background: The 16-item Meat Attachment Questionnaire (MAQ-16) assesses emotional and cognitive attachment to meat across four dimensions: hedonism, affinity, entitlement, and dependence. Recently validated in French, we aimed to develop and validate a shorter, four-item version (MAQ-4) to reduce participant burden.
Methods: In this 2023 observational study in the Rhône-Alpes region, 919 primary care patients were invited to complete the French MAQ-16 (MAQ-16).
Article Synopsis
- The text describes how a specific bacterium infects the upper airways of humans and uses toxins (PT and CyaA) to weaken the host's immune response.
- CyaA rapidly disrupts immune cell function by increasing cAMP levels, which inhibits the differentiation of inflammatory monocytes into effective macrophages and reduces their ability to acquire essential nutrients.
- Additionally, the study reveals that the effects of CyaA can be mitigated by a histone deacetylase inhibitor, suggesting that this toxin triggers epigenetic changes that help the bacterium evade the immune system and proliferate in the host's airway.