Publications by authors named "P Sebastian"
After the previous description and characterization of Theileria equi sensu stricto (Genotype A) in Argentina, the aim of the present study was to investigate the possible heterogeneity of 18 S rDNA genotypes circulating in this country. Therefore, blood samples from 18 horses from two different neighborhoods of Corrientes City, Corrientes Province, were analyzed for infection with Theileria species. Theileria DNA was detected in five samples (27.
View Article and Find Full Text PDFThis study aimed to evaluate A. marginale transstadial (TST) and transovarial transmission (TOT) by Amblyomma tonelliae through vector competence assays and analysis of natural infection in free-living ticks. This three-host tick species was chosen as model because it is a usual parasite of cattle in all their parasitic stages, making them potential vectors through TST or TOT.
View Article and Find Full Text PDF() promastigotes secrete exosomes that are crucial in host-pathogen interactions and intercellular communication by carrying parasite-specific molecules. Although the composition of cargos in exosomes is known, the effects of the unique metabolic repertoire on immunometabolism rewiring of macrophage polarization are poorly understood. Interestingly, we found the enrichment of polyamines (PAs) such as spermidine and putrescine in the -exosomes.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated tick-borne rickettsial bacteria in ticks collected from stray dogs in the Patagonian region of Argentina.
- A total of 90 ticks were examined, with 3 out of 33 tick pools testing positive for Anaplasmataceae bacteria, and partial DNA sequences confirming the presence of a bacteria linked to canine cyclic thrombocytopenia.
- Additionally, two tick samples were identified as part of the spotted fever group rickettsiae, marking the first molecular detection of these pathogens in this area of Argentina.
Aims: This study explores the evolution of organ donation from patients treated with extracorporeal-cardiopulmonary-resuscitation (ECPR) for refractory out-of-hospital-cardiac-arrest (OHCA) and evaluates the public health benefits of a mature ECPR program.
Methods: This retrospective, single-center study included OHCA patients (2016-2023) who had mostly initial shockable rhythms and were treated with ECPR. Organ donation rates from non-survivors through these years were analyzed.