Publications by authors named "P Schroeder"
Article Synopsis
- The All of Us Research Program (AoU) aims to collect a diverse dataset from over one million people in the USA to enhance research on human diseases, focusing on genetic and phenotypic information.
- This study developed and validated algorithms to identify cases of type 1 and type 2 diabetes using electronic health records and survey data, striving for improved accuracy in case-control studies.
- The results showed the EHR-only algorithm had a better association with type 1 diabetes genetic scores, while the EHR+ algorithm was superior for type 2 diabetes, identifying significantly more cases than previous definitions and providing new validated definitions for both diabetes types.
Background: Bovine tuberculosis (bTB) is the most important animal health concern in Wales. Annual testing across all cattle herds in Wales commenced in 2010. In 2017, a new geographic division of Wales was conceived, with bespoke cattle controls and eradication milestones reflecting the geographical heterogeneity of bTB distribution.
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- Type 2 diabetes (T2D) genome-wide association studies (GWASs) typically miss rare genetic variants due to limitations in previous imputation methods and insufficient whole-genome sequencing data.
- In a large-scale study involving over half a million individuals, researchers uncovered 12 new genetic variants linked to T2D, including a rare enhancer variant near the LEP gene that significantly increases risk.
- The study also analyzed ClinVar variants related to monogenic diabetes, identifying additional rare variants that affect T2D risk and offering new insights into the pathogenicity of certain variants previously deemed uncertain.
Plastic waste poses a significant challenge to achieving sustainable production and consumption of resources, particularly in sub-Saharan Africa where effective governance and waste management systems are lacking. In this paper, we develop an empirical understanding of the influence of public governance system on promoting circular economy (CE) for plastic actions among individuals. Through a survey of 1475 participants across five sub-Saharan African countries, we tested five hypotheses drawing on New Governance Theory and CE Action Recipe to explore the relationship between governance and individual's actions supporting CE for plastic.
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