Dosage dependency of intravitreal triamcinolone acetonide as treatment for diabetic macular oedema.

Aim: To evaluate the effect of different doses of intravitreal triamcinolone acetonide on diffuse diabetic macular oedema.

Methods: The prospective, randomised, double masked, clinical interventional study included 27 eyes (27 patients) with diffuse diabetic macular oedema. They were randomly divided into three study groups receiving an intravitreal injection of filtered triamcinolone acetonide of about 2 mg (n = 8 eyes), 5 mg (n = 10), or 13 mg (n = 9), respectively.

Triamcinolone acetonide concentration after filtration of the solvent agent.

Purpose: To determine the amount of triamcinolone acetonide and the preservative benzyl alcohol after filtration.

Design: Laboratory investigation.

Methods: The probes were prepared by two different hospital pharmacies.

Ranking of optic disc variables for detection of glaucomatous optic nerve damage.

Purpose: To describe optic disc variables assessed by evaluation of clinical optic disc photographs and to compare sensitivity and specificity of these optic disc parameters in identifying patients with ocular hypertension who have nerve fiber layer defects and normal visual fields and patients with visual field defects.

Methods: The study included 500 normal subjects, 132 patients with ocular hypertension with retinal nerve fiber layer defects and normal visual fields (preperimetric glaucoma), and 840 patients with glaucomatous visual field defects. Color stereo optic disc photographs were morphometrically evaluated.

[Retinal nerve fiber layer photography and papillometry in juvenile diabetes mellitus].

Chronic complications in diabetes mellitus are angiopathy and neuropathy. The appearance of microangiopathy on angiographical examination with fluorescein has been understood to be a very important prognostic sign in cases of juvenile diabetes mellitus. There are few reports of changes in the retinal nerve fiber layer or optic disc.