Publications by authors named "P Saz"
Sex Differences in Longitudinal Trajectories of Cognitive Aging in Zaragoza, Spain.
Am J Geriatr Psychiatry
October 2023
Article Synopsis
- The study aimed to document cognitive aging in healthy individuals aged 55 and older, focusing on differences between men and women.
- Conducted over 12 years in Zaragoza, Spain, the research involved 2,403 participants who underwent repeated assessments using the Mini-Mental State Examination (MMSE).
- Results showed women had lower MMSE scores and greater cognitive decline than men, highlighting different predictors for cognitive aging strategies based on sex.
Article Synopsis
- Parental history of dementia, especially from the mother, significantly increases the risk of developing dementia and Alzheimer's disease in offspring.
- A study involving over 17,000 older adults showed that those with a maternal history of dementia had a notably higher odds ratio for dementia and Alzheimer's, while paternal history did not show the same association.
- These findings suggest that knowing a person's maternal history could help identify individuals at greater risk for Alzheimer's, potentially guiding risk stratification in clinical settings.
Great inter-individual variability has been reported in the maintenance of cognitive function in aging. We examined this heterogeneity by modeling cognitive trajectories in a population-based longitudinal study of adults aged 55+ years. We hypothesized that (1) distinct classes of cognitive trajectories would be found, and (2) between-class differences in associated factors would be observed.
View Article and Find Full Text PDFBackground: Sense of Coherence (SOC) is defined as a tendency to perceive life experiences as comprehensible, manageable and meaningful. The construct is split in three major domains: Comprehensibility, Manageability, and Meaningfulness. SOC has been associated with successful coping strategies in the face of illness and traumatic events and is a predictor of self-reported and objective health in a variety of contexts.
View Article and Find Full Text PDFObjective: To explore the possibility that the mortality risk of mild cognitive impairment (MCI) as diagnosed using Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria (DSM-5-MCI) will be higher than using Petersen's criteria (P-MCI) and to report the population-attributable fraction (PAF) of mortality due to MCI.
Methods: A representative community sample of 4,803 individuals aged 55 or more years was interviewed and then followed for 17 years. Standardized instruments were used in the assessment, including the Geriatric Mental State-AGECAT, and research psychiatrists diagnosed P-MCI and DSM-5-MCI cases following operationalized criteria.