Publications by authors named "P Sattar"

Heart rate variability (HRV) analysis during sleep plays a key role for understanding autonomic nervous system function and assessing cardiovascular health. The UNICA Sleep HRV analysis (UNICA-HRV) tool is a novel, open-source MATLAB tool designed to fill the gap in current HRV analysis tools. In particular, the integration of ECG and HRV data with hypnogram information, which illustrates the progression through the different sleep stages, ease the computation of HRV metrics in polysomnographic recordings.

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Article Synopsis
  • REM Sleep Behavior Disorder (RBD) is linked to an increased risk of developing neurodegenerative diseases like Parkinson's and dementia, prompting a study of autonomic dysfunction in RBD patients.* -
  • The study used advanced methods to analyze sleep patterns and heart rate variability, revealing that RBD patients generally experience lower heart rate variability and are more likely to transition to lighter sleep stages.* -
  • Although RBD patients suffer from fragmented sleep and autonomic issues, those with Parkinson's displayed better sleep continuity, potentially due to relief from their PD symptoms during sleep.*
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Neuropathic pain (NP) following spinal cord injury (SCI) affects the quality of life of almost 40% of the injured population. The modified brain connectivity was reported under different NP conditions. Therefore, brain connectivity was studied in the SCI population with and without NP with the aim to identify networks that are altered due to injury, pain, or both.

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Background: The value of ultrasound enhancing agents (UEA) in patients undergoing transesophageal echocardiography (TEE) for the exclusion of left atrial appendage (LAA) thrombi prior to direct current cardioversion (DCCV) is evolving.

Methods: We retrospectively identified 88 consecutive TEEs, where a commercial UEA was used during LAA interrogation. De-identified non-enhanced (pre-UEA) and enhanced cine loop images (post-UEA) from the same subjects were randomly reviewed by four expert readers in a blinded fashion.

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Current standard of care following a percutaneous coronary intervention with stent placement necessitates the use of dual anti-platelet therapy with aspirin and commonly clopidogrel. There is a subset of patients who have a significant clopidogrel allergy and life-threatening hypersensitivity reactions. Desensitization is the process of inducing tolerance to a sensitizing agent via repeated exposure to the agent.

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