Publications by authors named "P Santavy"
Article Synopsis
- This study evaluates the results of concomitant cryo-ablation for treating atrial fibrillation (AF) in patients also undergoing cardiac surgery.
- Researchers analyzed data from 103 patients after they had a hybrid treatment involving radiofrequency catheter ablation performed 105 days post-surgery.
- The findings showed that a significant number of patients had successful isolation of pulmonary veins and conduction blocks, with specific areas exhibiting more gaps, indicating varied effectiveness in the ablation technique.
Aims: Data on the hybrid atrial fibrillation (AF) treatment are lacking in patients with structural heart disease undergoing concomitant CryoMaze procedures. The aim was to assess whether the timely pre-emptive catheter ablation would achieve higher freedom from AF or atrial tachycardia (AT) and be associated with better clinical outcomes than surgical ablation alone.
Methods And Results: The trial investigated patients with non-paroxysmal AF undergoing coronary artery bypass grafting and/or valve repair/replacement with mandatory concomitant CryoMaze procedure who were randomly assigned to undergo either radiofrequency catheter ablation [Hybrid Group (HG)] or no further treatment (Surgery Group).
Article Synopsis
- * The SurHyb study is a randomized trial comparing the effectiveness of surgical CryoMaze alone versus a combined approach of CryoMaze followed by radiofrequency catheter ablation after three months in patients with persistent atrial fibrillation.
- * This study aims to provide deeper insights into which treatment option is more effective for patients undergoing surgery, potentially improving outcomes for those with atrial fibrillation during heart surgeries.
The aim of this study was to describe and quantify pharmacokinetics of ampicillin used prophylactically in cardiac surgery both with and without cardiopulmonary bypass (CPB) using population pharmacokinetic analysis in order to propose an optimal dosing strategy. Adult patients undergoing cardiac surgery and treated with prophylactic dose of 2 g ampicillin were enrolled to this prospective study. Blood samples were collected according to the study protocol and ampicillin plasma concentrations were measured using HPLC/UV system.
View Article and Find Full Text PDFThe objectives of this study were to develop a population pharmacokinetic model of prophylactically administered cefazolin in patients undergoing cardiac surgery with and without the use of the cardiopulmonary bypass of both existing types-standard (ECC) and minimallyu invasive extracorporeal circulation (MiECC)-and to propose cefazoline dosing optimization based on this model. A total of 65 adult patients undergoing cardiac surgery were recruited to this clinical trial. A prophylactic cefazolin dose of 2 g was intravenously administered before surgery.
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