[Apheresis in dermatologic diseases].

This report discusses the different types of apheresis used to treat skin diseases and focuses specifically on photopheresis or ECP (extracorporeal photochemotherapy). ECP is a systemic immunomodulatory therapy used successfully to treat many different, mainly autoimmune diseases such as cutaneous T-cell lymphomas, graft-versus-host disease, systemic sclerosis, atopic dermatitis, and pemphigus vulgaris. It has also proved effective against graft rejection after transplant.

Papular-purpuric "gloves and socks" syndrome.

Papular-purpuric "gloves and socks" syndrome (PPGSS), is an acute dermatosis characterized by a papular-purpuric edematous rash in a distinct ''gloves and socks'' distribution often accompanied by fever, asthenia and lymphadenophaties. It is mainly caused by parvovirus B19 (B19V) but other viruses and drugs such as trimethoprim/sulfametaxol or chemotherapics may be involved. We describe a case of PPGSS with a serologically proven B19V infection in a 42-year-old Italian kindergarten teacher suffering from acute bacterial pharyngitis Immunoglobulin M by enzyme-linked immunosorbent assay (ELISA) to parvovirus B19 were positive.