Publications by authors named "P San"

Article Synopsis
  • Azathioprine is the first choice medicine for treating myasthenia gravis, but many people also use mycophenolate and methotrexate as alternatives.
  • A survey of 235 people found that azathioprine caused liver problems in 23% of users, mycophenolate led to diarrhea in 14%, and methotrexate made 18% feel tired.
  • Women generally have more side effects from these medicines, and azathioprine is often stopped more often than the other two due to these side effects, showing there’s a need for better treatments.
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Article Synopsis
  • * Patients often experience varying degrees of muscle weakness that can become severe and life-threatening if it affects muscles necessary for breathing and swallowing.
  • * The article discusses how complement system involvement contributes to the damage at the neuromuscular junction and reviews current therapies targeting this pathway, highlighting their efficacy and safety based on recent studies.
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Nanopesticides, particularly biosynthesized ones using organic reductants, hold great promise as a cost-effective and eco-friendly alternative to chemical pesticides. However, their efficacy on stored product pests, which can cause damage to dried grains, has not been extensively tested, especially on immature stages. Here, we biosynthesized six types of nanoparticles (NPs) using extracts from the fungus Fusarium solani: silver (AgNPs), selenium (SeNPs), silicon dioxide (SiONPs), copper oxide (CuONPs), titanium dioxide (TiONPs) and zinc oxide (ZnONPs) ranging in size from 8 to 33 nm.

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Purpose: Since the inception of tumor treating fields (TTFields) therapy as a Food and Drug Administration-approved treatment with known clinical efficacy against recurrent and newly diagnosed glioblastoma, various in silico modeling studies have been performed in an effort to better understand the distribution of applied electric fields throughout the human body for various malignancies or metastases.

Methods And Materials: Postacquisition attenuation-corrected positron emission tomography-computed tomography image data sets from 2 patients with ovarian carcinoma were used to fully segment various intrapelvic and intra-abdominal gross anatomic structures. A 3-dimensional finite element mesh model was generated and then solved for the distribution of applied electric fields, rate of energy deposition, and current density at the clinical target volumes (CTVs) and other intrapelvic and intra-abdominal structures.

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-Oligocarrageenan (OC) is an effective biostimulator and a protector against disease infections for plants. However, the effect of OC molecular weight (MW) on plant growth is not fully understood. In this work, OCs with three different MWs (42, 17 and 4 kDa) was prepared by varying the degradation reaction time using ascorbic acid as a reagent.

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