Publications by authors named "P Samperi"
Article Synopsis
- Noonan syndrome (NS) is an autosomal dominant genetic disorder affecting multiple organ systems and is often linked to a higher risk for certain cancers, particularly blood-related diseases.
- A case study is presented of a child diagnosed with transient myeloproliferative disorder at birth who later developed hyperdiploid B-cell precursor acute lymphoblastic leukemia and was found to have a specific germline mutation.
- After successful treatment and periods of remission, the same child developed juvenile myelomonocytic leukemia and received a hematopoietic stem cell transplant, prompting a review on the connection between NS and various hematological conditions.
Background: Diencephalic Syndrome is an atypical early manifestation of low-grade gliomas; so, it is important to detect it in patients that experience a failure to thrive despite adequate length growth and food intake. The purpose of this article is to focus attention on this rare but potentially dangerous cause of poor weight gain or stunting in childhood.
Materials And Methods: We describe four patients with Diencephalic Syndrome and low-grade gliomas who were evaluated in our institution from January 2017 to December 2021.
Article Synopsis
- Acute chest syndrome (ACS) is a common reason for hospitalizations in children with sickle cell disease (SCD), but knowledge about its best treatment practices is still lacking in many areas.
- A retrospective study examined ACS management in kids from 11 centers in Italy from 2013 to 2018, involving 122 children and 208 ACS episodes.
- The findings showed that while adherence to treatment guidelines was generally good, there were significant differences in care between specialized centers and general hospitals; thus, improvements in transfer protocols and treatment methods are needed.
Iron deficiency anemia (IDA) is the most frequent hematological disorder in children, with an incidence in industrialized countries of 20.1% between 0 and 4 years of age and 5.9% between 5 and 14 years (39 and 48.
View Article and Find Full Text PDF