Publications by authors named "P Salamanca-Bautista"
Introduction: Patients with heart failure in sinus rhythm may be at significant risk of major cardiovascular events, including cardiovascular death (CV death).
Objective: To assess CV mortality at a one-year follow up of those patients with heart failure and sinus rhythm, according to LVEF subgroups.
Methods: A prospective and multicentric study was conducted with patients in sinus rhythm included in the National Registry of Heart Failure.
Chronic heart failure (CHF) represents a challenge for the healthy system due to its high prevalence, high burden of morbidity and mortality, and high consumption of health resources. To address this problem, it is necessary to develop efficient management strategies that include both hospital care and outpatient care. The primary objective is to stabilize the patient and prevent decompensation, with the consequent improvement in quality of life, reduction in hospital admissions and emergency department care, and, consequently, reduction in healthcare costs.
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- Cardiac amyloidosis (CA) is common in elderly patients with heart failure (HF), but its prognosis compared to other HF causes is unclear.
- A study of 484 patients aged 65 and older found that 23.8% had CA; those with CA showed higher one-year mortality (33% vs. 14.9%) despite similar rates of emergency visits and readmissions.
- CA presence, alongside factors like chronic kidney disease and NT-proBNP levels, predicts worse outcomes, highlighting the need for early diagnosis and multidisciplinary care to improve patient prognosis.
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- The CLOROTIC trial studied the effects of adding hydrochlorothiazide (HCTZ) to furosemide in patients with acute heart failure, showing improved diuretic responses regardless of left ventricular ejection fraction (LVEF) levels.
- A total of 230 patients were analyzed, with results indicating that HCTZ led to better weight loss and diuretic measures within 72 hours, with no significant impacts on mortality or rehospitalization rates across different LVEF categories.
- The findings suggest that combining HCTZ with furosemide is an effective approach for enhancing diuretic effectiveness in acute heart failure patients, irrespective of their baseline LVEF.
Article Synopsis
- * It included 665 patients, and those with MA tended to be younger women with fewer health issues and better heart function, and they received more treatment with acetazolamide.
- * Although MA did not increase overall mortality risks, it was linked to a significantly higher rate of readmissions for heart failure within 30 and 90 days.