Publications by authors named "P SOULIER"
Background And Objectives: To report the prevalence of acute encephalopathy and outcomes in patients with severe coronavirus disease 2019 (COVID-19) and to identify determinants of 90-day outcomes.
Methods: Data from adults with severe COVID-19 and acute encephalopathy were prospectively collected for patients requiring intensive care unit management in 31 university or university-affiliated intensive care units in 6 countries (France, United States, Colombia, Spain, Mexico, and Brazil) between March and September of 2020. Acute encephalopathy was defined, as recently recommended, as subsyndromal delirium or delirium or as a comatose state in case of severely decreased level of consciousness.
Objectives: To describe early electrocardiogram (ECG) abnormalities after status epilepticus (SE) and evaluate their association with 90-day neurological outcomes.
Design: Retrospective analysis of a multicenter, national prospective registry between February 2018 and June 2020.
Setting: Sixteen ICUs in France, IctalGroup Research Network.
Introduction: Status epilepticus (SE) is a common life-threatening neurological emergency that can cause long-term impairments. Overall outcomes remain poor. Major efforts are required to clarify the epidemiology of SE and the determinants of outcomes, thereby identifying targets for improved management.
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- Uterine leiomyosarcomas and soft tissue leiomyosarcomas are rare tumors associated with poor outcomes and moderate response to chemotherapy; the latest update on the LMS-02 study suggests promising results for progression-free survival (PFS) and overall survival (OS) with a specific chemotherapy regimen.
- The study involved 108 patients, primarily with metastatic disease, receiving a treatment plan that included doxorubicin and trabectedin, with a notable percentage undergoing surgical resection after chemotherapy; results showed a median PFS of around 10.1 months and median OS of 34.4 months overall.
- Findings reinforce the efficacy of the doxorubicin and trab
An association of autoimmune hemolytic anemia with disseminated tuberculosis is an exceedingly rare entity. We describe herein a case of cold hemolytic autoimmune anemia associated with miliary tuberculosis resolved with blood transfusions, therapeutic plasma exchange, and antituberculous agents. We discuss the advantages of therapeutic plasma exchange at an early stage in the management of this condition.
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