Objectives: Circadian cues in children (sunlight, exercise, diet patterns) may be associated with health outcomes. The primary objective was to assess associations of daily cortisol fluctuations (morning, night) with cardiovascular health outcomes. A secondary objective was to determine if 1-year longitudinal changes in circadian cortisol levels are associated with longitudinal changes in health outcomes.
View Article and Find Full Text PDFPediatric obesity is a major health concern today, which pre-disposes individuals to metabolic syndrome (MS), and the risk of premature cardiovascular disease (CVD). Use of carotid intima media thickness (CIMT) is recognized as non-invasive way to assess vascular health. The objective of this study was to determine which MBS risk factors has an influence on increasing one's risk of an increased CIMT in children.
View Article and Find Full Text PDFObjective: To assess the effects of muscle strength, as determined by grip strength, on changes in health status in adolescents.
Study Design: Risk variables included excess body fat, elevated fasting glucose, high blood pressure, elevated serum triglycerides, and low high-density lipoprotein cholesterol. Multinomial logistic regression was used to quantify the odds of experiencing health maintenance (no risk factors identified at either time point) or health improvement (presence of ≥1 baseline risk factor and fewer or no risk factors at follow-up) over a 2-year period.
Background: Interleukin-15 (IL-15) is a myokine associated with muscle strength, possibly by attenuating protein breakdown. A variant in the alpha-receptor (IL-15Rα 1775 A>C, rs2228059) partially modulates the muscle strength and size response to resistance training. We examined if this polymorphism associated with habitual physical activity among European-American adults.
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