Publications by authors named "P S Tomlinson"

Purpose: The purpose of this paper was to explore interlocking questions relating to how we deal with drugs and medication in crisis residential mental health settings. In particular, it examines issues related to overly medical and simplistic explanations of the relationship between cannabis and psychosis, the positive effects of drugs, the effects of having standard rules for diverse groups of people and the concept of non-abstinent recovery.

Background: I have used mental health and addiction services for 25 years and I have 6 years' experience as a peer worker, working with many people who use drugs.

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Article Synopsis
  • - The text discusses the regulatory subunits of class IA phosphoinositide 3-kinase (PI3K) that interact with three catalytic subunits (p110α, p110β, p110δ) and how mutations in these subunits lead to specific diseases with unclear genotype-phenotype connections.
  • - Heterozygous loss-of-function mutations in p110α lead to SHORT syndrome, which is characterized by insulin resistance and short stature, while activating mutations cause APDS2 immunodeficiency, but patients don't show clear signs of p110α hyperactivation.
  • - Research on fibroblasts from APDS2 patients revealed no increase in PI3K signaling and decreased p110δ expression, indicating
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Phosphorus (P) fertilization practices and winter cover crops are promoted to protect water quality yet can potentially influence crop yield and profitability. This study examined the impacts of three P fertilizer management practices (no P, fall broadcast P, and spring injected P) and winter annual cover crop use on yields, net returns, and water quality in a no-till corn-soybean rotation. Treatments were replicated in a 4-yr field study where sediment, total P, and dissolved reactive P (DRP) losses in edge-of-field surface runoff were continuously monitored.

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Background: Continuous glucose monitoring (CGM) decreases fear of hypoglycemia (FOH) and improves glycemic control among those affected by type 1 diabetes (T1D). No studies to date have examined the impact of using do-it-yourself real-time continuous glucose monitoring (DIY RT-CGM) on psychological and glycemic outcomes.

Methods: Child-parent dyads were recruited for a multicentre randomized crossover trial.

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Aims: To describe the impact of a 12-month intervention using intermittently scanned continuous glucose monitoring (isCGM) on glycaemic control and glucose test frequency in adolescents and young adults with type 1 diabetes (T1D) and high-risk glycaemic control (HbA ≥75 mmol/mol [≥9.0%]).

Methods: In total, 64 young people (aged 13-20 years, 16.

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