Driving change: exploring cattle transporters' perspectives to improve worker and animal well-being.

The cattle industry has made considerable efforts to adopt more sustainable beef production practices. Still, the social pillar of sustainability-especially workforce well-being-often receives less attention than the environmental and economic pillars. There is also limited information about the perspectives of U.

Exploring the Role of Artificial Intelligence (AI)-Driven Training in Laparoscopic Suturing: A Systematic Review of Skills Mastery, Retention, and Clinical Performance in Surgical Education.

Artificial Intelligence (AI)-driven training systems are becoming increasingly important in surgical education, particularly in the context of laparoscopic suturing. This systematic review aims to assess the impact of AI on skill acquisition, long-term retention, and clinical performance, with a specific focus on the types of machine learning (ML) techniques applied to laparoscopic suturing training and their associated advantages and limitations. A comprehensive search was conducted across multiple databases, including PubMed, IEEE Xplore, Cochrane Library, and ScienceDirect, for studies published between 2005 and 2024.

Brief Report: Potential Gains in PrEP Coverage and Effect on Racial Disparities After Introduction of On-Demand and Long-Acting Injectable PrEP: Preferences of Men Who Have Sex With Men in the United States, 2021-2022.

Introduction: There are persistent race- and ethnicity-based disparities in HIV incidence among gay and bisexual men who have sex with men (GBMSM) in the United States, partially driven by inequities in distribution of pre-exposure prophylaxis (PrEP). We assessed how additional modalities of PrEP beyond daily oral might affect the uptake of PrEP and ongoing disparities in HIV incidence in the United States.

Methods: In an online survey of GBMSM in the United States, we presented participants with descriptions of each PrEP modality.

Data-driven insights to inform splice-altering variant assessment.

Disease-causing genetic variants often disrupt mRNA splicing, an intricate process that is incompletely understood. Thus, accurate inference of which genetic variants will affect splicing and what their functional consequences will be is challenging, particularly for variants outside of the essential splice sites. Here, we describe a set of data-driven heuristics that inform the interpretation of human splice-altering variants (SAVs) based on the analysis of annotated exons, experimentally validated SAVs, and the currently understood principles of splicing biology.

Longitudinal Surveillance of COVID-19 Antibodies in Pediatric Healthcare Workers.

Vaccines against COVID-19 target the spike protein. There is minimal information on longitudinal COVID-19 immune profiling in recovered versus naïve and vaccinated versus non-vaccinated healthcare workers (HCWs). This is a prospective longitudinal observational cohort of pediatric HCWs (pHCWs) conducted during 2020-2022 at an academic center, exploring the impact of COVID-19 vaccination on immunoglobulin G (IgG) antibody titers over time and cross-reactivity with other coronaviruses, including SARS-CoV-1, MERS-CoV, and seasonal coronaviruses (HCoV-HKU1 and HCoV-OC43).