Publications by authors named "P S Soni"
Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. Currently, there is no means to non-invasively identify NRF2 activation in living subjects. Here, we show that positron emission tomography imaging with the system x radiotracer, [F]FSPG, provides a sensitive and specific marker of NRF2 activation in orthotopic, patient-derived, and genetically engineered mouse models of NSCLC.
View Article and Find Full Text PDFVerification of Sub-national Claim for 'TB-free' Status of Rajsamand District, Rajasthan, India-2020.
Indian J Community Med
October 2024
Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis is an opportunistic infection that affects the lungs in humans. Caseload of TB has been deemed it endemic in various regions of the world and India is on top of that list. The Government of India has set out a goal to eliminate tuberculosis in India by the year 2025 with the help of the National Strategic Plan (NSP) 2017-25.
View Article and Find Full Text PDFEnhancing the Understanding of Anti-calcitonin Gene-related Peptide Monoclonal Antibodies in Chronic Migraine Prevention.
Clin Psychopharmacol Neurosci
November 2024
Article Synopsis
- - The study aimed to address the disconnect experienced by neurology residents during their first year in internal medicine by introducing a PGY-1 Director role to enhance resident well-being and connection to the program.
- - Surveys showed a marked decrease in burnout and an increase in feelings of support and validation among residents after the implementation of the PGY-1 Director role, with postintervention resident satisfaction significantly higher than preintervention.
- - The findings suggest that having a dedicated PGY-1 Director not only improves the wellness of trainees but also strengthens the relationship between the neurology and internal medicine departments, advocating for this model as a beneficial practice in residency programs.