Inhibition of Orthodontic Relapse by Local Application of Simvastatin-Loaded Gelatin Hydrogel in a Rabbit Model.

Objectives: This study aims to determine the effect of gelatin-simvastatin hydrogel application on bone remodelling during relapse.

Materials And Methods: Twenty-four rabbits (Oryctolagus cuniculus) were divided into a control group (n = 12) and a treatment group (n = 12). The lower incisors were subjected to orthodontic force and moved distally by an open coil spring.

The intrasulcular application effect of bisphosphonate hydrogel toward osteoclast activity and relapse movement.

Introduction: Orthodontic relapse occurs after orthodontic treatment and shifting of teeth to unfavorable positions. Bisphosphonates' effects on bone resorption and relapse prevention have been extensively investigated. However, topical administration, which results in local effect, is still a problem.

Effect of mangosteen peel extract as an antioxidant agent on the shear bond strength of orthodontic brackets bonded to bleached teeth.

Introduction: The number of patients who seek orthodontic treatment that may have a history of tooth bleaching is increasing over the time. Bleaching may influence the decrease of the bond strength of orthodontic brackets.

Objective: To determine and prove the effect of mangosteen peel (MP) extract to reverse the reduced shear bond strength (SBS) of orthodontic brackets after bleaching.

Enhancement of post-orthodontic tooth stability by carbonated hydroxyapatite-incorporated advanced platelet-rich fibrin in rabbits.

Objective: To evaluate the effect of carbonated hydroxyapatite-incorporated advanced platelet-rich fibrin on relapse and bone remodelling in rabbits.

Materials And Methods: Forty-five rabbits were divided into 3 groups (n = 15): a control group, carbonated hydroxyapatite (CHA) and carbonated hydroxyapatite-incorporated advanced platelet-rich fibrin (CHA-aPRF) group. The lower incisors were subjected to an orthodontic force of 50 cN.

The effect of fish oil on bone resorption following pulp exposure in rats.

The aim of this study was to determine whether treatment with fish oil may alter the periapical bone resorption following pulp exposure in rats. Untreated and pulp-exposed animals served as the negative and positive control, respectively. Other pulp-exposed animals were orally treated with fish oil at different concentrations and frequencies.