Publications by authors named "P S Plum"
Background/aim: The recently published Node-Reporting and Data System (Node-RADS) can aid the characterization of lymph nodes in cross-sectional imaging. This study investigated the Node-RADS system in computed tomography (CT) to characterize lymph nodes in esophageal cancer.
Patients And Methods: Overall, 126 patients (15 female, 11.
Importance: There is conflicting evidence regarding weekday dependent outcome in complex abdominal surgery, including pancreatic resections.
Objective: To clarify weekday-dependency of outcome after pancreatic resections in a comprehensive nationwide context.
Design: Retrospective cross-sectional study of anonymized nationwide hospital billing data (DRG data).
Background: Achalasia is a motility disorder of the esophagus and depending on its type, esophageal tubular hypo- or hypermotility can cause typical symptoms, such as dysphagia, chest pain, weight loss, or regurgitation. Clinical symptoms during initial diagnosis as well as over the course of therapy can be measured by the Eckardt score. Diagnostics include high-resolution manometry (HR manometry), (timed barium) esophagogram, upper gastrointestinal endoscopy, multiple rapid swallow response, and Endo-FLIP measurement.
View Article and Find Full Text PDFObjectives: The aim of this retrospective study was to collect epidemiological, clinical, laboratory, imaging, management, and follow-up data on cases of alveolar echinococcosis (AE) diagnosed and/or followed up within the Namur Hospital Network (NHN) in order to gather information on the challenges, pitfalls, and overall experience in the diagnosis and treatment of AE.
Methods: EchiNam was a multicenter retrospective study. Patients diagnosed and/or treated for probable or confirmed AE in the NHN between 2002 and 2023 were included in the study.
Article Synopsis
- Cholangiocarcinomas (CCA) are aggressive and poorly prognosed cancers, influenced by genetic changes such as MDM2 mutations; targeted therapies like Brigimadlin show potential benefits for specific patient groups.
- This study focused on 52 CCA patients to explore the relationship between MDM2 status and patient outcomes, using methods like FISH and IHC to analyze tumor samples.
- Results indicated that 5.8% of patients had MDM2 amplification, mostly in intrahepatic CCA, where improved survival rates were observed for those with amplification compared to those without.