An Algorithm for Automatic Generation and Evaluation of Leaflet Apparatus Models for Heart Valve Prostheses.

Unlabelled: is to develop and verify an algorithm for automatic generation of leaflet apparatus models for prosthetic heart valves, to optimize the basic parameters of the models in order to minimize the stress-strain state and maximize the geometric area of the orifice.

Materials And Methods: The suggested algorithm consists of three blocks: "Generator", "Modeling", "Analysis". The first block creates a three-dimensional model of the leaflet apparatus using the specified parameters (height, radius, thickness, degree of "sagging", angle of the free edge deviation).

Study of Biomechanics of the Heart Valve Leaflet Apparatus Using Numerical Simulation Method.

Unlabelled: was to study the complex biomechanics of the aortic valve prosthesis and to analyze the effect of frame mobility on the stress-strain state and geometry of the valve leaflet apparatus using a numerical simulation method, which reproduces the qualitative and quantitative results of its bench tests.

Materials And Methods: The object of the study was a commercial valve bioprosthesis UniLine (NeoCor, Russia), a three-dimensional mesh of which was obtained on the basis of computer microtomography with a subsequent analysis of its stress-strain state in the systole- diastole cycle by the finite element method in the Abaqus/CAE medium. The simulation was validated by comparing the results of numerical and bench simulation on the ViVitro Labs hydrodynamic system (ViVitro Labs Inc.