Publications by authors named "P S Chain"
Mucoromycota fungi and their Mollicutes-related endobacteria (MRE) are an ideal system for studying bacterial-fungal interactions and evolution due to the long-term and intimate nature of their interactions. However, methods for detecting MRE face specific challenges due to the poor representation of MRE in sequencing databases coupled with the high sequence divergence of their genomes, making traditional similarity searches unreliable. This has precluded estimations on the diversity of MRE associated with Mucoromycota.
View Article and Find Full Text PDFDiverse and complex microbiomes are found in virtually every environment on Earth. Bacteria and fungi often co-dominate environmental microbiomes, and there is growing recognition that bacterial-fungal interactions (BFI) have significant impacts on the functioning of their associated microbiomes, environments, and hosts. Investigating BFI remains a challenge, particularly when attempting to examine interactions at multiple scales of system complexity.
View Article and Find Full Text PDFArticle Synopsis
- Comparative analysis of genomes requires collecting and integrating high-quality data using standardized protocols.
- The Genomic Standards Consortium (GSC) works with researchers to create and uphold the MIxS reporting standard for genomic data.
- This document explains MIxS structure and terminology, guides users on finding necessary terms, and includes a practical example using soil metagenomes.