[The transfer of genes for Brown Rust resistance from Aegilops umbellulata Eig. to wheat (Triticum aestivum L.) genome].

The potential of a genome-substituted form Avrolata (AABBUU) as a genetic system in genomic and chromosome manipulations for gene transfer from the wild species Aegilops umbellulata Eig. (UU) to cultivated wheat was studied. It was shown that plants combining resistance to leaf brown rust with high productivity may be produced from this form by classical hybridization procedures.

Anti-oxidant capacity of spinal cord and erythrocytes of guinea pigs in case of experimental allergic encephalomyelitis and after disease suppression.

In the lumbar spinal cord of EAE guinea pigs a significant increase in SOD activity, lipid hydroperoxides content (more than 60%) and Fe2(+)-ascorbate-induced lipid peroxidation was observed. Multiple injections of cytochrome C-vitamin B2-vitamin PP (CV-combination) during the disease latent period resulted in suppression of EAE development. Supplementation with vitamin C, vitamin B12 or ATP eliminated this suppressive effect.

[Regulating and disturbing effects of alpha-tocopherol on lipid bilayers].

Using the high resolution 1H-NMR spectroscopy and spin-probes the influence of alpha-tocopherol on lipid bilayer microviscosity has been studied. It has been established that alpha-tocopherol shows the cholesterol-like action on the physical state of lipid bilayer: alpha-tocopherol increase microviscosity of unsaturated bilayers and decrease microviscosity of saturated bilayers. The character of alpha-tocopherol action is determined by the fatty acidic lipid composition but does not depend on the polar group structure of phospholipid molecule as cholesterol-like action of alpha-tocopherol is found itself in liposomes prepared both from phosphatidylcholine and phosphatidylethanolamine.

Inhibition of phospholipid hydrolysis by soluble phospholipase A2 in biological membranes of different origin after lipid peroxidation.

In peroxidized rat liver microsomal membranes phospholipid hydrolysis catalyzed by porcine pancreas phospholipase A2 was found to be inhibited. The extent of inhibition depended on the amount of lipid peroxidation products (MDA) accumulated in the membrane. This effect was not due to the direct action of lipid peroxidation products on the enzyme but to membrane modification.

The influence of starvation on some characteristics of the Ca2+ transport system and lipid content in rat liver mitochondria.

The effects of 48-hour starvation on some characteristics of the Ca2+ transport system as well as on lipid content and free fatty acids composition in rat liver mitochondria were determined. The ion fluxes in mitochondria in steady state and oscillations were measured using Ca2+, Sr2+ and H+ sensitive electrodes. The Ca2+ uptake in liver mitochondria was changed after starvation.